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Feb 13, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

MultiStem: Additional Phase I data

Additional data from an open-label, dose-escalation Phase I trial in 36 patients showed that a single injection of the highest dose of IV MultiStem given following allogeneic hematopoietic stem cell transplant (HSCT) led to a 100-day cumulative incidence of moderate to severe acute GvHD of 11%, which Athersys said "compares favorably" with historical clinical experience for this patient population (40-60% incidence rate for grade II-IV GvHD for historical control). No patient developed severe GvHD and there were no graft failures over the 100-day period following HSCT. Furthermore, relapse-free survival at...

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