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Jan 30, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Saridegib: Interim Phase Ib/II data

Infinity stopped an international Phase Ib/II trial after an interim analysis of the double-blind Phase II portion of the trial in 122 patients with previously untreated metastatic pancreatic cancer showed that once-daily oral saridegib plus gemcitabine would not meet the primary endpoint of median OS vs. placebo plus gemcitabine. The company said there was a higher rate of progressive disease in the saridegib plus gemcitabine arm. Specifically, the median OS for saridegib plus gemcitabine was...

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