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Jan 23, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Tykerb: Phase III data

Researchers at Massachusetts General Hospital Cancer Center and colleagues reported data from the open-label, international Phase III NeoALTTO trial in 455 HER2-positive primary breast cancer patients with tumors >2 cm in diameter showing that a significantly greater proportion of patients receiving Herceptin trastuzumab plus Tykerb lapatinib achieved a pCR at the time of surgery, the primary endpoint, vs. Herceptin alone (51.3% vs. 29.5%, p=0.0001). pCR was defined as no invasive cancer in the breast or only non-invasive in situ...

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