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Jan 02, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Aliskiren: Phase III discontinued

Novartis discontinued the double-blind, placebo-controlled, international Phase III ALTITUDE trial in 8,606 Type II diabetics with renal impairment after an independent DMC concluded that patients were "unlikely to benefit" from the addition of once-daily 300 mg aliskiren to standard of care (SOC) anti-hypertensive treatment. Additionally, aliskiren plus SOC led to...

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