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12:00 AM
Aug 15, 2011
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Daclizumab high-yield process: Phase IIb data

Top-line data from the double-blind, international Phase IIb SELECT trial in 600 patients showed that once-monthly 150 and 300 mg subcutaneous daclizumab each met the primary endpoint of ARR compared to placebo. Specifically, low- and high-dose daclizumab reduced ARR by 54% and 50%, respectively, vs. placebo at 1 year (p<0.0001 and p=0.0002, respectively). Compared to placebo, low- and high-dose daclizumab also met the secondary endpoints of significantly reducing the cumulative number of new gadolinium-enhancing lesions between weeks 8-24 (69% and 78%, respectively); the number of new or newly-enlarging...

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