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12:00 AM
Aug 08, 2011
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Taliglucerase alfa: Additional Phase III data

Top-line data from 26 evaluable patients in an open-label, crossover, international Phase III trial showed that mean hemoglobin and platelet counts, spleen volume and liver volume remained stable after patients switched from Cerezyme imiglucerase to an equivalent dose of IV taliglucerase alfa every 2 weeks for 9 months. One patient experienced a hypersensitivity reaction. The trial was originally designed to enroll 15 patients, but was expanded to include 30 patients as a result of the shortage of enzyme replacement therapy for Gaucher's patients. Genzyme Corp., a subsidiary...

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