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12:00 AM
Aug 08, 2011
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Laquinimod: Phase III data

Top-line data from the double-blind, international Phase III BRAVO trial in 1,331 patients showed that once-daily 0.6 mg oral laquinimod missed the primary endpoint of significantly reducing ARR from baseline to 2 years vs. placebo (0.29 vs. 0.37, p=0.075). However, a pre-specified sensitivity analysis that adjusted for dissimilarities in 2 baseline MRI characteristics - the percent of patients with gadolinium-enhanced lesions and the volume of T2 lesions - between placebo, laquinimod and the active control

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