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12:00 AM
Apr 18, 2011
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Dimebon latrepirdine: Development discontinued

Medivation and Pfizer discontinued development of Dimebon to treat HD after top-line data from the double-blind, international Phase III HORIZON trial in 403 patients showed that thrice-daily 20 mg oral Dimebon missed the co-primary endpoints of significantly improving cognition as measured by the MMSE and global function as measured by CIBIC-plus at 6 months vs. placebo (p=0.39 and p=0.84, respectively). Dimebon was generally...

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