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12:00 AM
Apr 11, 2011
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Contrave: Additional Phase III data

Data from 182 patients in the ambulatory blood pressure monitoring (ABPM) sub-study of the double-blind, placebo-controlled, U.S. Phase III COR-II (NB-303) trial in 1,496 patients showed that patients treated with Contrave maintained normal 24-hour circadian patterns over 52 weeks of treatment. Additionally, Contrave-treated patients in the sub-study had significantly greater weight loss vs. placebo at week 52 (7.5% vs. 2.5%, p<0001). Contrave also significantly reduced waist circumference (7.5 vs. 2.3 cm, p<0.001)...

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