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12:00 AM
Apr 04, 2011
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Telaprevir: Interim Phase II data

Interim data from 59 treatment-naïve patients with chronic HCV genotype 1 infection in the ongoing, open-label, U.S. and New Zealand Phase II ZENITH trial showed that twice-daily 100 and 400 mg VX-222 plus 1,125 mg telaprevir, Pegasys peginterferon alfa-2a and Copegus ribavirin led to undetectable HCV RNA levels at week 2 in 38% (n=29) and 57% (n=30) of patients, respectively. Additionally, the low- and high-dose combination regimens produced undetectable HCV RNA levels at both weeks 2 and 8 in 38% and 50% of patients, respectively. Patients with undetectable virus at weeks...

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