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12:00 AM
 | 
Apr 04, 2011
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Motesanib: Phase III data

Top-line data from the double-blind Phase III MONET1 trial in 1,090 patients with advanced non-squamous NSCLC showed that once-daily 125 mg oral motesanib plus carboplatin and paclitaxel as first-line therapy missed the primary endpoint of significantly improving OS vs. placebo plus carboplatin and paclitaxel (p=0.14). Adverse events included hypertension, gastrointestinal and gallbladder events, fatigue and hematological events.

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