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12:00 AM
Feb 28, 2011
 |  BC Week In Review  |  Clinical News  |  Clinical Results

VX-770: Phase II data

The double-blind, U.S. Phase II DISCOVER trial in 140 patients with 2 copies of the delta F508 CFTR mutation showed that twice-daily 150 mg oral VX-770 missed the co-primary endpoint of significantly improving the mean absolute change in FEV1 from baseline to week 16 vs. placebo. Specifically, the mean absolute improvement in FEV1 at week 16...

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