Defibrotide: Expanded access program interim data

Interim data from the ongoing, U.S. expanded access program of defibrotide in 104 patients with severe VOD with multi-organ failure showed that 31 patients achieved a complete response and 33 patients survived to day 100 post-stem cell transplantation. Additionally, patients who were not on dialysis or were not ventilator dependent at the start of the study had a higher complete response rate compared to patients who were (41% vs. 23%). Data were presented at the American Society of Hematology meeting in Orlando. ...