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12:00 AM
Nov 22, 2010
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Anacetrapib: Phase III data

The double-blind, international Phase III DEFINE trial in 1,623 patients with CHD or CHD risk-equivalent disease who were already receiving statins and were at a guideline-established LDL-C goal showed that once-daily 100 mg anacetrapib for 76 weeks met the primary endpoint of significantly reducing LDL-C from baseline to week 24 vs. placebo (36 vs. 5 mg/dL, p<0.001). Specifically, anacetrapib reduced LDL-C from 81 mg/dL at baseline to 45 mg/dL at...

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