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12:00 AM
Sep 13, 2010
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Arbaclofen: Phase II data

In the per protocol (PP) population (n=25) of an open-label, U.S. Phase II trial, STX209 met the primary endpoint of significantly improving irritability subscale scores on the ABC-I from baseline to week 8 (p<0.001). STX209 also significantly improved global and specific neurobehavioral outcomes from baseline, including the Social Withdrawal subscale of the ABC (ABC-SW) (p<0.001) and the ABC-Total scale (p<0.001). Additionally, STX209 significantly improved investigators' assessments of Clinical Global Impressions of Improvement (CGI-I) (p=0.001) and Severity (CGI-S) (p=0.002)...

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