Australian researchers uncover perlecan’s role in the tumor stroma

An Australian team has uncovered perlecan as the latest in a growing list of new therapeutic targets in the tumor stroma, and the molecule may be playing a role in pancreatic tumor invasiveness.

In a paper published in Nature Communications in August, Garvan Institute of Medical Research researchers and colleagues uncovered a link between p53 mutations in pancreatic cancer cells and increased metastasis. ...