A telltale mouse to guide AAV design for gene editing
A mouse model puts in vivo AAV activity under the microscope and reveals unexpected opportunities for gene editing
A study from Spark co-founder Beverly Davidson suggests AAV vectors can reach more tissues than previously thought, opening up new opportunities and guidelines for AAV-mediated gene editing.
In a Nature Communications paper, Davidson’s team described a mouse model that reported transient, low levels of AAV transduction with more sensitivity than conventional methods. While such