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Fc sugar additions control fetal transfer of maternal antibodies

Duke, Harvard/Weill Cornell teams find sugar residues determine antibody transfer to the fetus

Two groups have identified determinants of antibody transfer across the placenta, paving a way to maternal delivery of therapies that boost neonatal protection against infections.

The teams homed in on IgG Fc sugar additions as factors controlling antibody transfer to fetuses, which are key

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