Binding the extracellular matrix to target brain tissue

Binding the extracellular matrix exposed by disrupted BBB to target brain tissue

Attaching biologics to an antigen receptor derived from a fish that preferentially binds the brain's extracellular matrix could enable targeted drug delivery to the CNS.

A University of Wisconsin-Madison team found that lamprey-derived immune molecules called variable lymphocyte receptors (VLRs) could target brain

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