BioCentury
ARTICLE | Translation in Brief

Liu’s new strategy could make gene editing insertions more precise

How David Liu's latest Cas9 construct improves gene insertion

May 28, 2019 9:58 PM UTC

The latest study from CRISPR veteran David Liu describes a new tweak to the gene editing machinery that could better position it to correct, rather than just disrupt, gene targets.

Using CRISPR to disrupt a gene's expression is well-validated and being evaluated in the clinic, but CRISPR companies and researchers are still trying to figure out how to insert corrected genetic sequences more efficiently and safely. ...