ARTICLE | Translation in Brief
Template-free CRISPR for correcting pathogenic duplications
UMass scientists have shown how template-free CRISPR could treat diseases caused by DNA duplication mutations
May 23, 2019 7:12 PM UTC
A UMass med school team has shown how template-free CRISPR could repair pathogenic DNA duplications and identified over a hundred disease-associated mutations as targets for the new method.
Author Scot Wolfe, a professor of molecular, cell and cancer biology at the University of Massachusetts Medical School, said the strategy could be used to develop therapies for many untreated diseases...