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9:04 AM
Dec 20, 2018
 |  BC Innovations  |  Translation in Brief

Beyond T cell counts

How functional TCR profiling could aid selection of cancer treatments

While strategies to increase the efficacy of immune checkpoint inhibitors have largely been focused on boosting overall T cell count in the tumor microenvironment, researchers at the Netherlands Cancer Institute (NKI) found that antigen specificity of the T cells must also be taken into account, and the team plans to form a spinout to develop the findings.

In a December letter published in Nature Medicine, the researchers found that in high-grade serous ovarian cancer...

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