BioCentury
ARTICLE | Translation in Brief

ATAC of the DREADDs

Cal Tech team combines existing tech to selectively control neural circuits

July 31, 2018 9:18 PM UTC

Scientists from the California Institute of Technology have combined ultrasound waves with gene and drug therapies to selectively and non-invasively control neural circuits. The approach could be used to treat neurologic and psychiatric diseases and validate roles for specific neuronal circuits.

The adaptation of the three existing technologies, which the team dubbed acoustically targeted chemogenetics (ATAC), was described in a study published in Nature Biomedical Engineering in July...