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Tuning thresholds

How Rice University researchers are tuning biosensors of inflammation

Synthetic biologists at Rice University have figured out how to tune naturally occurring bacterial biosensors to detect clinically relevant levels of target molecules. The group intends to use the approach to engineer gut microbes that can diagnose -- and, one day, possibly treat -- GI diseases.

Bacteria express a wide range of two-component biosensors wherein one component detects a signal in the environment and

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