MOA the same

A comparative metabolomics method could identify MOAs for antibiotics

An ETH Zurich-led team has developed a high throughput method of comparative metabolomics that can predict MOAs for antibiotics, and used it to suss out how a library of previously uncharacterized GSK compounds killed bacteria.

While the team's Science Translational Medicine study showed proof of concept in mycobacterial culture, the method could predict MOAs of compounds against any pathogenic bacteria, bypassing the

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