CRISPR to the point

As improvements to CRISPR-based gene editing continue apace, a Harvard University leader in the space has produced an updated version of a technology he described only a year ago for accurately generating point mutations without cutting DNA.

In a paper published in Nature Communications, a team led by Harvard professor David Liu -- a co-founder of gene editing company Editas Medicine Inc. (NASDAQ:EDIT) -- outlined a high-fidelity version of its gene editing tool Base Editor 3 (BE3) that introduced fewer off-target edits than earlier iterations of the technology. ...