Two faces of tau

Can tau be used to protect against β-amyloid toxicity?

Contrary to the dogma that β-amyloid triggers Alzheimer’s disease (AD) by inducing phosphorylation of the neuronal protein tau, an Australian team has shown that the process can in fact be protective rather than pathogenic. In defining the mechanism, the team uncovered MAP kinase 12 (MAPK12; ERK-3; p38γ) as a new target involved in early stage progression of the disease.

“It is

Read the full 609 word article

User Sign In