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ARTICLE | Translation in Brief

Fat links

Monitoring neurotensin to predict, evade and link obesity and cancer

June 16, 2016 7:00 AM UTC

Although neurotensin promotes fat uptake, satiety and cancer cell growth, the hormone's instability has made it difficult to measure in the clinic or connect directly to human disease. Using an assay from sphingotec GmbH on a stable peptide proxy, researchers at the University of Kentucky and Lund University have shown the hormone is a causative driver of obesity that could serve as a predictive marker for the disease.

In addition, the team thinks neurotensin (NTS) could be a key link between obesity and cancer or other indications that have been associated with the hormone's action from human studies...