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Knowing when to fold

How unfolded protein stress plays a common role in Type I and II diabetes

A team from the Flanders Institute for Biotechnology (VIB) has linked two genes involved in the unfolded protein stress response to the fragility of pancreatic β cells involved in both Type I and Type II diabetes, and developed a mouse model that could provide a new tool for identifying drugs for both forms of the disease.

While Type I diabetes involves autoimmune

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