Master of autism
How a CPEB4 isoform imbalance could be the key to modeling polygenic autism
The discovery of a master regulator of autism risk genes has yielded the first mouse model of the form of the condition that accounts for about 90% of patients, and could spark a new way of thinking about how to model polygenic diseases.
Like many neurological conditions, the vast majority of autism cases are idiopathic, not driven by a single mutation but by the complex interplay of small genetic risk factors as well as environmental influences. ...
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