BioCentury
ARTICLE | Tools & Techniques

Postmodern ART

How HIV therapy is moving beyond ART

March 31, 2016 7:00 AM UTC

The next frontier in HIV therapy is moving patients beyond antiretroviral therapy (ART), which involves daily cocktails of compounds that block replication and spread of the virus, taken either as separate or combined formulations. Because HIV hides out in a latent state in immune and other cells, creating a dormant pool dubbed a "reservoir," there's a danger it can get activated at any time, which means the drugs must be taken for life.

Select strategies being pursued to replace ART or allow patients to come off therapy altogether are outlined below...