ARTICLE | Targets & Mechanisms
How glycoRNA could go from surprise discovery to therapeutic target
What it will take for newly discovered glycoRNA to become translational white space
October 18, 2019 12:02 AM UTC
The first evidence that sugars decorate RNA could open up new therapeutic opportunities in autoimmunity and cancer, but industry won't invest until structural data and disease associations emerge.
Beyond the growing taxonomy of RNA subtypes defined by structure and function -- including microRNA (miRNA), long non-coding RNA (lncRNA), circular RNA (circRNA), small nuclear RNA (snRNA) and Y RNA -- an expanding roster of RNA modifications are adding complexity to the molecular class. ...