BioCentury
ARTICLE | Targets & Mechanisms

Unsaturated remyelination

Case Western spins out Convelo to develop remyelination drugs

August 17, 2018 1:46 AM UTC

Enzymes downstream in cholesterol biosynthesis could provide new ways to stimulate remyelination that avoid the baggage of previously identified multiple sclerosis targets, according to a group at Case Western. The university is spinning out Convelo Therapeutics Inc. to translate the idea.

Marketed therapies for MS work via immune suppression, which slows disease progression but does not regenerate lost myelin. ...