BioCentury
ARTICLE | Targets & Mechanisms

Oxitope’s oxidation play

A UCSD group links oxidized lipids to atherosclerosis and spins out Oxitope Inc.

August 3, 2018 12:01 AM UTC

A trio of papers from a UCSD group has found a connection between oxidized lipids and inflammation in atherosclerosis, osteoporosis and ischemia injury, breathing new life into the once popular “oxidation hypothesis” of atherosclerosis.

The authors are spinning out Oxitope Inc. to develop a mAb that selectively targets oxidized forms of lipids. ...