Exosomes deliver

Codiak BioSciences Inc. founder Raghu Kalluri has published the first animal data demonstrating exosomes can be used as drug delivery vehicles to treat cancer -- not just diagnose it. The findings also mark the unveiling of Codiak’s lead therapeutic program: exosomes that carry an siRNA against mutant KRAS to treat pancreatic cancer.

Exosomes first gained traction as a handle for non-invasive diagnostics because they are shed by cells into the bloodstream, and carry with them nucleic acids and proteins that can provide a window into the biology of the cells that shed them...