ARTICLE | Targets & Mechanisms
Solving triptolide
November 29, 2012 8:00 AM UTC
University of Minnesota researchers have developed a water-soluble prodrug of the poorly soluble cancer therapeutic triptolide that could give a second life to the plant-derived compound.1 Minneamrita Therapeutics LLC holds a license to the new molecule and plans to start a Phase I trial within six months.
Triptolide is a diterpenoid triepoxide derived from the traditional Chinese medicine plant Tripterygium wilfordii...