BioCentury
ARTICLE | Targets & Mechanisms

Niemann-Pick(ing) on Ebola

September 8, 2011 7:00 AM UTC

Teams in Europe and the U.S. have identified a host protein called

Niemann-Pick disease type C1 that is required for Ebola virus to enter cells,1,2 and both groups are developing small molecules that target the entry protein. Both teams also are pursuing challenge studies in animals with the U.S. Army Medical Research Institute of Infectious Diseases...