Computing towards a cure
How CHDI is working with IBM’s computing power to model Huntington’s disease
With the help of IBM, the Huntington’s disease not-for-profit CHDI and its partners have been bringing artificial intelligence to HD research and developing models of disease progression that integrate data from the level of genes to clinical outcomes.
The partnership aims to drive drug discovery by marrying CHDI Foundation Inc.’s network and access to patient data with IBM Corp.’s expertise in AI to generate models that will generate a steady stream of new projects for drug developers to pick up.
The early fruits have yielded three studies on modeling disease progression and folding of HTT - the protein mutated in HD -- and more publications planned in 2018.
CHDI is a nonprofit whose mission is to facilitate development of treatments for HD by funding collaborations among research groups with different strengths, including academic investigators, CROs, pharmas and biotechs.
President Robi Blumenstein told BioCentury CHDI wanted to move beyond the