How Zymeworks aims to take on Roche’s $10B HER2 franchise

Zymeworks is going head to head with one of the biggest commercial cancer franchises -- Roche’s Herceptin trastuzumab and Perjeta pertuzumab -- as it pursues clinical proof-of-concept for its protein engineering platform.

Pivotal readouts in 2022 from its lead bispecific program, along with additional data from the biotech’s first ADC, will provide the first glimpse of whether Zymeworks Inc.'s technologies can generate best-in-class molecules that outperform combinations of individual mAbs. ...