Breaking bad biofilms

Synspira’s glycopolymers target mechanisms driving decline in pulmonary disorders

Synspira LLC is developing glycopolymers against pulmonary disorders by targeting three mechanisms that exacerbate pulmonary decline: bacteria themselves, the mucus and biofilms that protect them and inflammation that leads to lasting tissue damage.

Synspira in-licensed its technology from therapeutic polysaccharide company Synedgen Inc. in 2017 to develop polycationic glycopolymers in pulmonary indications. Lead product SNSP113 is a derivative of poly-N-acetyl-glucosamine to treat pulmonary exacerbations in

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