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ARTICLE | Emerging Company Profile

Evoking exosomes

Evox is making exosomes that can deliver therapies to the brain

February 1, 2017 6:43 PM UTC

Exosomes are emerging as one of the newest technologies for creating diagnostics and delivering therapeutics, primarily in cancer. Evox Therapeutics Ltd. is joining the growing list of start-ups, using science from exosome pioneer Matthew Wood to expand the field to the CNS.

In 2011, Wood’s group published a study in Nature Biotechnology showing it could engineer exosomes to selectively deliver siRNAs to the brain and knock down BACE1, a key target in Alzheimer’s disease. Wood is an Evox co-founder and professor of neuroscience at University of Oxford...