BioCentury
ARTICLE | Emerging Company Profile

Accelerating stem cells

How Accellta Ltd. can rapidly manufacture stems cells in suspension

September 24, 2015 7:00 AM UTC

Growing human pluripotent stem cells on adherent surfaces is inefficient, expensive and often doesn't yield homogeneous cell preparations. Accellta Ltd. has suspension-based, feeder-free methods that produce homogeneous pluripotent stem cells and differentiate them in sufficient quantities for multiple research and therapeutic applications.

Adherent culture systems are often unwieldy because they require feeder cells to provide growth factors, animal serum-derived supplements in the medium, enzymes to detach the cells from the adherent surfaces and multiple changes of culture medium. Accellta CEO Itzchak Angel said the company has two technologies that eliminate the need for all those requirements: Singles, for growing large numbers of stem cells in single-cell suspension; and Maxells, for growing small clumps of cells and rapidly differentiating them in suspension. ...