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 | 
Feb 05, 2019
 |  BC Innovations  |  Distillery Therapeutics

Hematology

INDICATION: Immunodeficiency

Cell culture studies identified two allosteric stabilizers of mutant MALT1 that could help treat combined immunodeficiency in patients harboring the loss-of-function W580S mutation of MALT1, which results in low B cell counts. In vitro screening of a small molecule library followed by optimization of the...

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