5:51 AM
Jan 29, 2019
 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Staphylococcus

In vitro, cell culture and mouse studies identified three TNC-based fusion proteins against S. aureus leukocidin ED or S. aureus γ-hemolysin AB that could help prevent and treat Staphylococcus infections. Screening of libraries of centyrins, which are protein scaffolds derived from the FN3 consensus-binding sequence of human TNC, against S. aureus leukocidins in binding and human neutrophil-based activity assays yielded...

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