12:32 PM
 | 
Sep 10, 2018
 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Encephalopathy

Patient sample and mouse studies suggest inhibiting the JAK/STAT1 pathway, the interaction between MCP-1 and CCR2, or phagocyte activation could help treat Rasmussen encephalitis. In postmortem brain samples from patients, levels of phosphorylated STAT1 and MCP-1 and the number of activated phagocytes were higher than in samples from patients with non-neurological diseases. In a mouse model of Rasmussen encephalitis, inhibiting...

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