10:50 AM
 | 
Aug 29, 2018
 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Malaria

In vitro, cell culture and mouse studies identified asparagine ethylenediamine-based inhibitors of Plasmodium falciparum proteasome subunit β type 5 that could help treat malarial infection. Screening of a library of tool compound proteasome inhibitors and in vitro enzymatic activity assays identified seven asparagine...

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