ARTICLE | Distillery Therapeutics
Neurology
August 1, 2018 8:10 PM UTC
Mouse studies identified a PPP1R15B inhibitor that could help treat HD. Chemical synthesis and in vitro testing of guanabenz analogs yielded a compound that bound PPP1R15B with a Kd of 33 nM and inhib...
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Medical Research Council Laboratory of Molecular Biology (MRC LMB)