2:39 PM
 | 
Jul 10, 2018
 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Liver cancer

In vitro, cell culture and mouse studies identified a SALL4-derived peptide inhibitor of the SALL4-RBBP4 interaction that could help treat hepatocellular carcinoma (HCC). Chemical synthesis and in vitro testing of analogs of a SALL4-derived peptide yielded a compound that inhibited SALL4-RBBP4 binding with an...

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