BioCentury
ARTICLE | Distillery Therapeutics

Neurology

April 18, 2018 4:02 PM UTC

Mouse studies suggest inhibiting MGLL could help treat chemotherapy-induced neuropathic pain. In a mouse model of paclitaxel-induced neuropathic pain, two tool compound MGLL inhibitors decreased mechanical allodynia compared with vehicle. Next steps could include testing MGLL inhibitors in additional models of chemotherapy-induced neuropathic pain...