11:12 AM
 | 
Feb 21, 2018
 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Non-small cell lung cancer (NSCLC)

Cell culture and mouse studies suggest combining MCL1 inhibitors with inducers of double-strand break stress could help treat NSCLC. In an irradiated human NSCLC cell line, MCL1 knockout decreased repair of radiation-induced double-strand breaks compared with normal MCL1 expression. Also in the cell...

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